Research Post-Doctoral Fellow in Genetic Epidemiology/Statistical Genetics
Location: Oakland, California
Type: Full Time
Preferred Education: Doctorate
Years of Experience:
Less than 2
Our team at the Kaiser Permanente Northern California Division of Research (DOR) is seeking a Research Post-Doctoral Fellow (100% FTE for at least 2 years) interested in research projects related to human genetics and genomics, with a focus on identifying genetic factors which influence complex traits, diseases and their treatments. The Research Post-Doctoral Fellow will work under the supervision of Dr. Hélène Choquet (Research Scientist and Principal Investigator) on a variety of NIH-funded projects including: (a) studying the genetics of eye diseases, such as glaucoma; (b) investigating the genetic factors underlying nonmelanoma skin cancers; and (c) studying the genetic mechanisms that drive the development of abdominal hernias.
These projects will integrate advanced genetic and genomic approaches, using an exceptional resource consisting of a cohort of more than 100,000 adults with genome-wide genotype data that are linked to participants’ electronic health records, to address the following goals: 1) advance our understanding of disease etiology; 2) identify potential molecular targets for the development of treatment; and 3) predict future disease risk based on genetic information, along with demographic, clinical, and behavioral factors.
Roles and responsibilities of the Fellow include conducting independent genetic and statistical analyses, writing manuscripts for peer-reviewed publication and presentation of abstracts at scientific meetings and assisting in overall study conduct (e.g., design requirements for databases and data validation) and in grant writing and submission.
To apply, please go to kp.org/careers, job #970569 or submit a cover letter, CV, and the names of three references to Hélène Choquet, PhD at firstname.lastname@example.org (Research Scientist and Principal Investigator). We will accept materials until the position is filled.
The successful candidate will ideally have methodological training in statistical genetics, genetic epidemiology, and/or bioinformatics, programming skills, content knowledge in human genetics, strong writing skills, experience in the publication of scientific manuscripts, and interest and experience in grant writing.
Ph.D. or equivalent graduate degree in statistical genetics or genetic epidemiology, and/or bioinformatics.
Ability to work independently with appropriate supervision while being a team player
Strong communication and writing skills are required.
Expertise in statistical programming (ideally in R) is strongly preferred.
Experience analyzing genome-wide association study (GWAS), sequencing, gene expression or other ‘omics’ datasets will be highly valued.
Experience with development of genome-wide polygenic risk scores (GPS) is a plus.
Kaiser Permanente is an integrated health care delivery system with a diverse membership in eight regions across the United States. In the Northern California region, Kaiser Permanente includes a health plan with over 4.5 million members, 21 hospitals and 260 ambulatory medical offices, and a multi-specialty physician group with more than 9,500 physicians. The Division of Research, which is part of Kaiser Permanente Northern California, has more than 600 people on staff, including 57 faculty-level investigators with 350 ongoing, funded projects on a wide range of health research topics. In 2020, the Division's research portfolio included over $125 million in grants awarded by the National Institutes of Health, other federal agencies, private foundations, industry, and Kaiser Permanente. Our investigators have made contributions in many research areas, including disease prevention, patient engagement, chronic illness management, clinical trials, the role of genes and the environment in health, health informatics, and delivery science. Founded in 1961, the Division's research program has been built on a base of externally-funded, rigorous epidemiologic and health services investigati...on. The postdoc may also take advantage of other ongoing training programs within Kaiser Permanente such as the Early Stage Investigators and Delivery Science programs, to facilitate career development.